The DASH Diet, Sodium Intake and Blood Pressure Trial (DASH-Sodium)
Identifieur interne : 00A927 ( Main/Exploration ); précédent : 00A926; suivant : 00A928The DASH Diet, Sodium Intake and Blood Pressure Trial (DASH-Sodium)
Auteurs : Laura P. Svetkey [États-Unis] ; Frank M. Sacks [États-Unis] ; Eva Obarzanek [États-Unis] ; William M. Vollmer [États-Unis] ; Lawrence J. Appel [États-Unis] ; Pao-Hwa Lin [États-Unis] ; Njeri M. Karanja [États-Unis] ; David W. Harsha [États-Unis] ; George A. Bray [États-Unis] ; Mikel Aickin [États-Unis] ; Michael A. Proschan [États-Unis] ; Marlene M. Windhauser [États-Unis] ; Janis F. Swain [États-Unis] ; Phyllis B. Mccarron [États-Unis] ; Donna G. Rhodes [États-Unis] ; Reesa L. Laws [États-Unis]Source :
- Journal of the American Dietetic Association [ 0002-8223 ] ; 1999.
Abstract
Abstract: The DASH Diet, Sodium Intake and Blood Pressure Trial (DASH-Sodium) is a multicenter, randomized trial comparing the effects of 3 levels of sodium intake and 2 dietary patterns on blood pressure among adults with higher than optimal blood pressure or with stage 1 hypertension (120–159/80–95 mm Hg). The 2 dietary patterns are a control diet typical of what many Americans eat, and the DASH diet, which, by comparison, emphasizes fruits, vegetables, and low-fat dairy foods, includes whole grains, poultry, fish, and nuts, and is reduced in fats, red meat, sweets, and sugar-containing beverages. The 3 sodium levels are defined as higher (typical of current US consumption), intermediate (reflecting the upper limit of current US recommendations), and lower (reflecting potentially optimal levels). Participants are randomly assigned to 1 of the 2 dietary patterns using a parallel group design and are fed each of the 3 sodium levels using a randomized crossover design. The study provides participants with all of their food during a 2-week run-in feeding period and three 30-day intervention feeding periods. Participants attend the clinic for 1 meal per day, 5 days per week, and take home food for other meals. Weight is monitored and individual energy intake adjusted to maintain baseline weight. The primary outcome is systolic blood pressure measured at the end of each intervention feeding period. Systolic blood pressure is compared across the 3 sodium levels within each diet and across the 2 diets within each sodium level. If effects previously observed in clinical trials are additive, sodium reduction and the DASH diet together may lower blood pressure to an extent not as yet demonstrated for nonpharmacologic treatment. The DASH-Sodium results will have important implications for the prevention and treatment of high blood pressure. J Am Diet Assoc. 1999;99(suppl):S96–S104.
Url:
DOI: 10.1016/S0002-8223(99)00423-X
Affiliations:
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Svetkey</name><affiliation wicri:level="2"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>L. P. Svetkey is an associate professor of medicine and nephrology and the director of the Duke Hypertension Center, and P-H. Lin is an assistant research professor in the Department of Medicine and the Sarah W. Stedman Center for Nutritional Studies, at the Duke University Medical Center, Durham, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Sacks, Frank M" sort="Sacks, Frank M" uniqKey="Sacks F" first="Frank M" last="Sacks">Frank M. Sacks</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>F. M. Sacks is an associate professor of nutrition in the Harvard School of Public Health, and of medicine at the Harvard Medical School, Boston, Mass</wicri:regionArea><wicri:noRegion>Mass</wicri:noRegion></affiliation></author><author><name sortKey="Obarzanek, Eva" sort="Obarzanek, Eva" uniqKey="Obarzanek E" first="Eva" last="Obarzanek">Eva Obarzanek</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>E. Obarzanek is a research nutritionist at the National Heart, Lung, and Blood Institute, Bethesda, Md, where M. A. Proschan is a mathematical statistician for the Office of Biostatistics Research</wicri:regionArea><wicri:noRegion>where M. A. Proschan is a mathematical statistician for the Office of Biostatistics Research</wicri:noRegion></affiliation></author><author><name sortKey="Vollmer, William M" sort="Vollmer, William M" uniqKey="Vollmer W" first="William M" last="Vollmer">William M. Vollmer</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>W. M. Vollmer and M. Aickin are senior investigators, N. M. Karanja is an investigator, and R. L. Laws is a senior research systems analyst for Kaiser Permanente Center for Health Research, Portland, Ore</wicri:regionArea><wicri:noRegion>Ore</wicri:noRegion></affiliation></author><author><name sortKey="Appel, Lawrence J" sort="Appel, Lawrence J" uniqKey="Appel L" first="Lawrence J" last="Appel">Lawrence J. Appel</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>L. J. Appel is an associate professor of medicine, epidemiology, and international health at the Johns Hopkins University, Baltimore, Md, where P. B. McCarron is a research nutritionist at the ProHealth Clinical Center</wicri:regionArea><wicri:noRegion>where P. B. McCarron is a research nutritionist at the ProHealth Clinical Center</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Pao Hwa" sort="Lin, Pao Hwa" uniqKey="Lin P" first="Pao-Hwa" last="Lin">Pao-Hwa Lin</name><affiliation wicri:level="2"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>L. P. Svetkey is an associate professor of medicine and nephrology and the director of the Duke Hypertension Center, and P-H. Lin is an assistant research professor in the Department of Medicine and the Sarah W. Stedman Center for Nutritional Studies, at the Duke University Medical Center, Durham, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Karanja, Njeri M" sort="Karanja, Njeri M" uniqKey="Karanja N" first="Njeri M" last="Karanja">Njeri M. Karanja</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>W. M. Vollmer and M. Aickin are senior investigators, N. M. Karanja is an investigator, and R. L. Laws is a senior research systems analyst for Kaiser Permanente Center for Health Research, Portland, Ore</wicri:regionArea><wicri:noRegion>Ore</wicri:noRegion></affiliation></author><author><name sortKey="Harsha, David W" sort="Harsha, David W" uniqKey="Harsha D" first="David W" last="Harsha">David W. Harsha</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>D. W. Harsha is an associate professor and chief of the Body Composition Department, M. M. Windhauser is an associate professor of research, and G. A. Bray is the executive director of and professor at the Pennington Biomedical Research Center, Baton Rouge, La</wicri:regionArea><wicri:noRegion>La</wicri:noRegion></affiliation></author><author><name sortKey="Bray, George A" sort="Bray, George A" uniqKey="Bray G" first="George A" last="Bray">George A. Bray</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>D. W. Harsha is an associate professor and chief of the Body Composition Department, M. M. Windhauser is an associate professor of research, and G. A. Bray is the executive director of and professor at the Pennington Biomedical Research Center, Baton Rouge, La</wicri:regionArea><wicri:noRegion>La</wicri:noRegion></affiliation></author><author><name sortKey="Aickin, Mikel" sort="Aickin, Mikel" uniqKey="Aickin M" first="Mikel" last="Aickin">Mikel Aickin</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>W. M. Vollmer and M. Aickin are senior investigators, N. M. Karanja is an investigator, and R. L. Laws is a senior research systems analyst for Kaiser Permanente Center for Health Research, Portland, Ore</wicri:regionArea><wicri:noRegion>Ore</wicri:noRegion></affiliation></author><author><name sortKey="Proschan, Michael A" sort="Proschan, Michael A" uniqKey="Proschan M" first="Michael A" last="Proschan">Michael A. Proschan</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>E. Obarzanek is a research nutritionist at the National Heart, Lung, and Blood Institute, Bethesda, Md, where M. A. Proschan is a mathematical statistician for the Office of Biostatistics Research</wicri:regionArea><wicri:noRegion>where M. A. Proschan is a mathematical statistician for the Office of Biostatistics Research</wicri:noRegion></affiliation></author><author><name sortKey="Windhauser, Marlene M" sort="Windhauser, Marlene M" uniqKey="Windhauser M" first="Marlene M" last="Windhauser">Marlene M. Windhauser</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>L. J. Appel is an associate professor of medicine, epidemiology, and international health at the Johns Hopkins University, Baltimore, Md, where P. B. McCarron is a research nutritionist at the ProHealth Clinical Center</wicri:regionArea><wicri:noRegion>where P. B. McCarron is a research nutritionist at the ProHealth Clinical Center</wicri:noRegion></affiliation></author><author><name sortKey="Swain, Janis F" sort="Swain, Janis F" uniqKey="Swain J" first="Janis F" last="Swain">Janis F. Swain</name><affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>J. F. Swain is the nutrition research manager for the General Clinical Research Center and Department of Endocrinology and Hypertension at Brigham and Women's Hospital, Boston</wicri:regionArea><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mccarron, Phyllis B" sort="Mccarron, Phyllis B" uniqKey="Mccarron P" first="Phyllis B" last="Mccarron">Phyllis B. Mccarron</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>L. J. Appel is an associate professor of medicine, epidemiology, and international health at the Johns Hopkins University, Baltimore, Md, where P. B. McCarron is a research nutritionist at the ProHealth Clinical Center</wicri:regionArea><wicri:noRegion>where P. B. McCarron is a research nutritionist at the ProHealth Clinical Center</wicri:noRegion></affiliation></author><author><name sortKey="Rhodes, Donna G" sort="Rhodes, Donna G" uniqKey="Rhodes D" first="Donna G" last="Rhodes">Donna G. Rhodes</name><affiliation wicri:level="3"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>D. G. Rhodes is a research nutritionist at the Welch Center for Prevention, Epidemiology, and Clinical Research, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Laws, Reesa L" sort="Laws, Reesa L" uniqKey="Laws R" first="Reesa L" last="Laws">Reesa L. Laws</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>W. M. Vollmer and M. Aickin are senior investigators, N. M. Karanja is an investigator, and R. L. Laws is a senior research systems analyst for Kaiser Permanente Center for Health Research, Portland, Ore</wicri:regionArea><wicri:noRegion>Ore</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of the American Dietetic Association</title><title level="j" type="abbrev">YJADA</title><idno type="ISSN">0002-8223</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1999">1999</date><biblScope unit="volume">99</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="supplement">S</biblScope><biblScope unit="page" from="S96">S96</biblScope><biblScope unit="page" to="S104">S104</biblScope></imprint><idno type="ISSN">0002-8223</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0002-8223</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The DASH Diet, Sodium Intake and Blood Pressure Trial (DASH-Sodium) is a multicenter, randomized trial comparing the effects of 3 levels of sodium intake and 2 dietary patterns on blood pressure among adults with higher than optimal blood pressure or with stage 1 hypertension (120–159/80–95 mm Hg). The 2 dietary patterns are a control diet typical of what many Americans eat, and the DASH diet, which, by comparison, emphasizes fruits, vegetables, and low-fat dairy foods, includes whole grains, poultry, fish, and nuts, and is reduced in fats, red meat, sweets, and sugar-containing beverages. The 3 sodium levels are defined as higher (typical of current US consumption), intermediate (reflecting the upper limit of current US recommendations), and lower (reflecting potentially optimal levels). Participants are randomly assigned to 1 of the 2 dietary patterns using a parallel group design and are fed each of the 3 sodium levels using a randomized crossover design. The study provides participants with all of their food during a 2-week run-in feeding period and three 30-day intervention feeding periods. Participants attend the clinic for 1 meal per day, 5 days per week, and take home food for other meals. Weight is monitored and individual energy intake adjusted to maintain baseline weight. The primary outcome is systolic blood pressure measured at the end of each intervention feeding period. Systolic blood pressure is compared across the 3 sodium levels within each diet and across the 2 diets within each sodium level. If effects previously observed in clinical trials are additive, sodium reduction and the DASH diet together may lower blood pressure to an extent not as yet demonstrated for nonpharmacologic treatment. The DASH-Sodium results will have important implications for the prevention and treatment of high blood pressure. J Am Diet Assoc. 1999;99(suppl):S96–S104.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Caroline du Nord</li><li>Maryland</li><li>Massachusetts</li></region><settlement><li>Baltimore</li><li>Boston</li></settlement></list><tree><country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Svetkey, Laura P" sort="Svetkey, Laura P" uniqKey="Svetkey L" first="Laura P" last="Svetkey">Laura P. Svetkey</name></region><name sortKey="Aickin, Mikel" sort="Aickin, Mikel" uniqKey="Aickin M" first="Mikel" last="Aickin">Mikel Aickin</name><name sortKey="Appel, Lawrence J" sort="Appel, Lawrence J" uniqKey="Appel L" first="Lawrence J" last="Appel">Lawrence J. Appel</name><name sortKey="Bray, George A" sort="Bray, George A" uniqKey="Bray G" first="George A" last="Bray">George A. Bray</name><name sortKey="Harsha, David W" sort="Harsha, David W" uniqKey="Harsha D" first="David W" last="Harsha">David W. Harsha</name><name sortKey="Karanja, Njeri M" sort="Karanja, Njeri M" uniqKey="Karanja N" first="Njeri M" last="Karanja">Njeri M. Karanja</name><name sortKey="Laws, Reesa L" sort="Laws, Reesa L" uniqKey="Laws R" first="Reesa L" last="Laws">Reesa L. Laws</name><name sortKey="Lin, Pao Hwa" sort="Lin, Pao Hwa" uniqKey="Lin P" first="Pao-Hwa" last="Lin">Pao-Hwa Lin</name><name sortKey="Mccarron, Phyllis B" sort="Mccarron, Phyllis B" uniqKey="Mccarron P" first="Phyllis B" last="Mccarron">Phyllis B. Mccarron</name><name sortKey="Obarzanek, Eva" sort="Obarzanek, Eva" uniqKey="Obarzanek E" first="Eva" last="Obarzanek">Eva Obarzanek</name><name sortKey="Proschan, Michael A" sort="Proschan, Michael A" uniqKey="Proschan M" first="Michael A" last="Proschan">Michael A. Proschan</name><name sortKey="Rhodes, Donna G" sort="Rhodes, Donna G" uniqKey="Rhodes D" first="Donna G" last="Rhodes">Donna G. Rhodes</name><name sortKey="Sacks, Frank M" sort="Sacks, Frank M" uniqKey="Sacks F" first="Frank M" last="Sacks">Frank M. Sacks</name><name sortKey="Swain, Janis F" sort="Swain, Janis F" uniqKey="Swain J" first="Janis F" last="Swain">Janis F. Swain</name><name sortKey="Vollmer, William M" sort="Vollmer, William M" uniqKey="Vollmer W" first="William M" last="Vollmer">William M. Vollmer</name><name sortKey="Windhauser, Marlene M" sort="Windhauser, Marlene M" uniqKey="Windhauser M" first="Marlene M" last="Windhauser">Marlene M. Windhauser</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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